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The Leukemia/Bone Marrow Transplant Program of BC

For Patients & Families
Diagnostic Tests & Procedures

Urine Test

There are several urine tests of which two are commonly performed:

  1. 24-hour urine for creatinine clearance
  2. Urine for culture and sensitivity

24-hour Creatinine Clearance Urine Test

The creatinine clearance test is used to see how well the kidneys work. Creatinine is a waste product put out in urine by the kidneys. The test compares the level of creatinine in the blood with the amount of creatinine put out by the kidneys in a 24-hour period. A decreased rate of clearance means the kidneys are not working as well as they should. Chemotherapy treatments may have to be changed.

24-hour urine collections might also be done for protein measurement, especially in patients with multiple myeloma or graft-versus-host disease.

Patient Preparation & Procedure

This is a routine test started soon after you come in to hospital. You will be given instructions on when the test and 24-hour period will begin. At the start of the test, you will need to empty your bladder and throw this urine away. Record the time.

After this, all urine must be saved for the next 24 hours in large plastic bottles. It’s easiest to keep these bottles in your bathroom. However, if you have to go out for an appointment, take a bottle with you.

It is essential that all urine be collected during this 24-hour period. If any urine is accidentally thrown away or mixed with stool, the test will have to be started again.

At the end of the 24 hours, you will urinate one last time and save it in one of the bottles. The bottles will then be sent to the lab.

Be sure to drink plenty of liquids during the test!

The plastic bottles can be obtained at your local lab or at the VGH Outpatient Lab. The VGH Outpatient Lab is located on the Ground Floor in the Gordon and Leslie Diamond Health Care Centre.

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Urine Test for Culture & Sensitivity

In this test, urine is tested for organisms that may cause an infection. This test can also tell the physician which are the best antibiotics to use if there is an infection.

Patient Preparation & Procedure

Ideally, the sample is collected in the morning because urine is more concentrated then.

The vulva or tip of the penis must be cleaned well with soap and water and dried with sterile gauze. This helps to prevent any bacteria normally found on the skin from getting into the urine sample.

A clean catch or midstream sample is needed. Patients must begin to urinate into the toilet, stop, and then continue to urinate into a sterile plastic jar. When finished, patients should tell the nurse because the sample must be sent to the lab right away.

Some patients find it hard to urinate into the small container and may want to wear plastic gloves. Gloves are kept in all patient rooms.

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