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The Leukemia/Bone Marrow Transplant Program of BC

For Patients & Families
Complications & Side Effects

Bladder Effects (Hemorrhagic Cystitis)

The urinary tract is a common area for infection in the general population as well as BMT patients. However, in BMT patients bladder inflammation caused by the use of cyclophosphamide prior to most transplants can often occur. This can resemble a urinary tract infection with symptoms including burning and frequent urination as well as visible blood or blood clots in the urine. This complication is called hemorrhagic cystitis.


To prevent this, large volumes of IV fluids are given while you receive cyclophosphamide in order to flush out the bladder. You are also encouraged to urinate as soon as you get the urge in order to prevent the drug from sitting in the bladder for too long.

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